Trismus is a jaw disorder that leads to a reduction in the jaw’s range of motion. Ultimately, trismus can lead to malnutrition, social isolation, depression, chronic pain, and in severe cases, trismus can even be fatal as a result of a compromised airway. There are many possible etiologies of trismus, such as oral radiation, oral surgery, maxillofacial trauma, central nervous system infection, upper motor neuron lesions from stroke or traumatic brain injury, and certain pharmaceutical drugs. Some etiologies of trismus are stimulable to jaw mobility exercises, while other forms of trismus are not stimulable to jaw mobility exercises. Certain forms of trismus may only respond to pharmaceutical or surgical interventions. Treatment courses are dependent upon the patient's trismus etiology, medical situation, and goals. Thus, it is crucial for SLPs to understand the different origins, pathophysiology of trismus, and various treatment pathways in order to provide safe and effective therapy services to patients.